1-Boc-b-oxo-3-piperidinepropanoic acid ethyl ester

1-Boc-b-oxo-3-piperidinepropanoic acid ethyl ester - Names and Identifiers

Name	tert-Butyl 3-(3-ethoxy-3-oxopropanoyl)piperidine-1-carboxylate
Synonyms	CIVENTICHEM CV-4401 tert-Butyl 3-(3-ethoxy-3-oxopropanoyl) 1-BOC-3-(2-ETHOXYCARBONYL-ACETYL)PIPERIDINE Ethyl 3-Oxo-3-(1-Boc-3-piperidyl)propanoate 1-Boc-b-oxo-3-piperidinepropanoic acid ethyl ester 1-BOC-BETA-OXO-3-PIPERIDINEPROPANOIC ACID ETHYL ESTER TERT-BUTYL 3-(3-ETHOXY-3-OXOPROPANOYL)PIPERIDINE-1-CARBOXYLATE tert-Butyl 3-(3-ethoxy-3-oxopropanoyl)piperidine-1-carboxylate 3-(2-Ethoxycarbonylacetyl)piperidine-1-carboxylic acid tert-butyl ester 3-(2-ETHOXYCARBONYL-ACETYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
CAS	877173-80-3
InChI	InChI=1/C15H25NO5/c1-5-20-13(18)9-12(17)11-7-6-8-16(10-11)14(19)21-15(2,3)4/h11H,5-10H2,1-4H3

1-Boc-b-oxo-3-piperidinepropanoic acid ethyl ester - Physico-chemical Properties

Molecular Formula	C15H25NO5
Molar Mass	299.36
Density	1.113g/cm³
Boling Point	386.1°C at 760 mmHg
Flash Point	187.3°C
Vapor Presure	3.64E-06mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.479

1-Boc-b-oxo-3-piperidinepropanoic acid ethyl ester - Introduction

tert-Butyl 3-(3-ethoxy-3-oxopropanoyl)piperidine-1-carboxylate is an organic compound with the formula C16H27NO5. The following is a description of some of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: colorless liquid
-Molecular weight: 309.39g/mol
-Melting Point: Not Applicable
-Boiling point: approximately 200°C
-Density: approximately 1.008g/cm³

Use:
- tert-Butyl 3-(3-ethoxy-3-oxopropanoyl)piperidine-1-carboxylate is commonly used as a starting material, intermediate or catalyst in organic synthesis.
-It has certain application value in the field of medicine and can be used to synthesize some drug molecules or pharmaceutical intermediates.
-It can also be used to synthesize biologically active compounds, such as antibacterial agents, anti-tumor drugs, etc.

Preparation Method:
The preparation method of tert-Butyl 3-(3-ethoxy-3-oxopropanoyl)piperidine-1-carboxylate can be carried out by the following steps:
1. Dissolve piperidine in ethanol.
2. Add oxo acetone and hydrochloric acid.
3. After completion of the reaction, tert-butanol was added and neutralized.
4. After filtration, concentration and crystallization, the target product is obtained.

Safety Information:
- tert-Butyl 3-(3-ethoxy-3-oxopropanoyl) is piperidine-1-carboxylate irritating and should be rinsed with plenty of water immediately after contact with skin or eyes.
-In the process of use, should wear appropriate protective gloves and glasses protection. At the same time, make sure to operate in a well-ventilated place.
-Avoid contact with strong oxidants and keep away from open flames or high temperatures.
-When storing, it should be sealed and kept away from fire and heat sources.

Please note that the above information is for reference only. If you need to know more about the properties, uses, preparation methods and safety information of this compound, it is recommended to refer to the relevant chemical literature or consult a professional.

Last Update：2024-04-09 21:11:58